PATHOLOGICAL ROLES OF UBIQUITINATION AND DEUBIQUITINATION SYSTEMS IN SEPSIS-INDUCED MYOCARDIAL DYSFUNCTION

Sepsis-induced myocardial dysfunction (SIMD) is a severe complication of sepsis, characterized by impaired cardiac function and high mortality rates.Despite significant advances in understanding sepsis pathophysiology, the molecular mechanisms underlying SIMD remain incompletely elucidated.Ubiquitination and deubiquitination, critical post-translat

Unilateral destructive brain lesions of early development can result in compensatory thickening of the ipsilateral cranial vault.The aim of this study was to determine the frequency of these bone changes among patients with epilepsy and precocious destructive lesions, and Outdoor End Table whether a relationship exists between these changes and epi